Description of image       

Description of image       
Search by Gene  



    
      Gene:  ARHGEF12
      GeneID:  ENSG00000196914
      Chrom:  11
      Start position:  120336413
      End position:  120489937
      Pathway:  C-type lectin receptor signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0617496
      Number of nsSNPs:  2
      nsSNPs in gene:  rs148969251
rs2305013
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.84  (Driver)
 
Recurrently deleted in 4 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Not specified
      JensenLab PubMed score:  448.33  (Percentile rank: 90.03%)
      PubTator score:  58.42  (Percentile rank: 70.28%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  N/A
      Tractability (antibody):  

    

Contact us | | Terms & Conditions.
Copyright © 2024 University of Pennsylvania. All Rights Reserved.

Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital