Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
MMP27ENSG00000137675                                                                                                                                    
CHEK1ENSG00000149554                                                                                                                                    
WNK1ENSG00000060237      1                                                                                                                              
IAPPENSG00000121351                                                                                                                                    
TUBA1CENSG00000167553                                                                                                                                    
RDH5ENSG00000135437                                                                                                                                    
CDK2ENSG00000123374                                                                                                                                    
CYP27B1ENSG00000111012                                                                                                                                    
APAF1ENSG00000120868                                      1                                                                                              
TXNRD1ENSG00000198431                                                                                                                                    
NUAK1ENSG00000074590                                                                                                                                    
ACACBENSG00000076555                                                                      1                                                              
LATS2ENSG00000150457                                                                          1                                                          
PARP4ENSG00000102699                                                                                                                                    
SLC25A30ENSG00000174032                                                                                                                                    
GRK1ENSG00000185974                                                                                                                                    
RNASE4ENSG00000258818                                                                                                                                    
ANGENSG00000214274                                                                                                                                    
RNASE8ENSG00000173431                                                                                                                                    
GMPR2ENSG00000100938                                                                                                                                    

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