Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
FJX1ENSG00000179431                                                                                                                                    
ALDH3B2ENSG00000132746                                                                                                                                    
PRKAG1ENSG00000181929                                                                                                                                    
MARSENSG00000166986                                                                                                                                    
MAPKAPK5ENSG00000089022                                                                                                                                    
RB1ENSG00000139687      1    1    1                    1    1                        1    1    1        1                    1    1                    1          
DHRS7ENSG00000100612                                                                                                                                    
PKMYT1ENSG00000127564                                                                                                                                    
PHKG2ENSG00000156873                                                                                                                                    
CES2ENSG00000172831                                                                                                                                    
CYB5D2ENSG00000167740                                                                                                                                    
SLC25A35ENSG00000125434                                                                                                                                    
TAF15ENSG00000270647                                                                                                                                    
HCRTENSG00000161610                                                                                                                                    
PYYENSG00000131096                                                                                                                                    
SERPINB13ENSG00000197641                                                                                                                                    
HSD11B1LENSG00000167733                                                                                                                                    
SLC25A23ENSG00000125648                                                                                                                                    
UBA2ENSG00000126261                                                                                                                                    
CYP2A6ENSG00000255974                                                                                                                                    

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