TCDA PDG

  FCG

  Home

  PDGs

  Search

  Expression

  Copy Number

  Mutation

  Transcript Fusion

  Download

  Help

  About

PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
Showing page 41	first page \| previous page \| next page \| last page

HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
polymeric immunoglobulin receptor	ENSG00000162896	PIGR	chr1:206928518-206946466:-	Tbio	173.686
endoglin	ENSG00000106991	ENG	chr9:127815012-127854756:-	Tbio	1538.83
ATPase Na+/K+ transporting subunit alpha 1	ENSG00000163399	ATP1A1	chr1:116372668-116410261:+	Tclin	111.308
syntaxin 1A	ENSG00000106089	STX1A	chr7:73699206-73719672:-	Tbio	324.303
fibrillin 1	ENSG00000166147	FBN1	chr15:48408306-48645849:-	Tbio	923.987
proteasome 26S subunit, non-ATPase 14	ENSG00000115233	PSMD14	chr2:161308038-161411717:+	Tbio	38.1066
nucleotide binding oligomerization domain containing 2	ENSG00000167207	NOD2	chr16:50693603-50733077:+	Tclin	1555.79
microtubule affinity regulating kinase 1	ENSG00000116141	MARK1	chr1:220528183-220664461:+	Tchem	844.226
TYRO3 protein tyrosine kinase	ENSG00000092445	TYRO3	chr15:41557675-41583586:+	Tchem	104.955
lysine acetyltransferase 5	ENSG00000172977	KAT5	chr11:65711996-65719604:+	Tbio	191.323
G protein-coupled receptor 35	ENSG00000178623	GPR35	chr2:240605431-240631259:+	Tchem	39.1016
gremlin 1, DAN family BMP antagonist	ENSG00000166923	GREM1	chr15:32717974-32745107:+	Tbio	119.087
angiogenin	ENSG00000214274	ANG	chr14:20684177-20698971:+	Tbio	502.482
phenylalanine hydroxylase	ENSG00000171759	PAH	chr12:102836885-102958410:-	Tclin	1445.31
signal transducer and activator of transcription 1	ENSG00000115415	STAT1	chr2:190964358-191020960:-	Tchem	1350.87
methionyl-tRNA synthetase 1	ENSG00000166986	MARS	chr12:57475445-57517569:+	Tchem	121.542
AXL receptor tyrosine kinase	ENSG00000167601	AXL	chr19:41219203-41261766:+	Tchem	521.372
collagen type V alpha 2 chain	ENSG00000204262	COL5A2	chr2:189031896-189179879:-	Tbio	71.0868
TNF receptor superfamily member 4	ENSG00000186827	TNFRSF4	chr1:1211326-1214138:-	Tbio	199.418
CD74 molecule	ENSG00000019582	CD74	chr5:150401637-150412929:-	Tchem	193.653

Showing page 41

first page | previous page | next page | last page

  TCGA

  GDC

  NCI