GPR35
| Official symbol: | GPR35 |
| Full name: | G protein-coupled receptor 35 |
| Location: | 2q37.3 |
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| Entrez ID: | 2859 |
| Ensembl ID: | ENSG00000178623 |
| Summary: | |
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Overall distribution
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Tissue specific distribution
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| Expression restricted in 2 cancer type(s) | |
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Overall distribution
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Tissue specific distribution
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| Gscore (Amp): | 0.00 | | Gscore (Del): | 1.33 (Driver) |
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| Recurrently deleted in 6 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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Overall
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Tissue specific
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| Total fusion occurrence: | 5 |
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| Fusions detected in 3 cancer type(s) |
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Overall
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Tissue specific
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CRISPR: STRONGLY SELECTIVE
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| Functional class: | G protein-coupled receptor |
| JensenLab PubMed score: | 64.15 (Percentile rank: 66.19%) |
| PubTator score: | 39.10 (Percentile rank: 63.89%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
