Mutation
The putative cancer-causing GESPs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Overall_Mscore | No. of Cancer Types |
| glutamic-oxaloacetic transaminase 2 | ENSG00000125166 | GOT2 | chr16:58707131-58734357:- | 0.02 | 1 |
| fibroblast growth factor receptor 1 | ENSG00000077782 | FGFR1 | chr8:38411138-38468834:- | 0.02 | 1 |
| calsyntenin 1 | ENSG00000171603 | CLSTN1 | chr1:9729026-9824526:- | 0.02 | 1 |
| protein kinase N2 | ENSG00000065243 | PKN2 | chr1:88684222-88836255:+ | 0.01 | 1 |
| transmembrane 9 superfamily member 1 | ENSG00000100926 | TM9SF1 | chr14:24189143-24195687:- | 0.01 | 1 |
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