Mutation
The putative cancer-causing GESPs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
| Showing page 5 |
first page | previous page | next page | last page |
| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Overall_Mscore | No. of Cancer Types |
| discs large MAGUK scaffold protein 1 | ENSG00000075711 | DLG1 | chr3:197042560-197299300:- | 0.06 | 1 |
| angiomotin | ENSG00000126016 | AMOT | chrX:112774503-112840815:- | 0.06 | 1 |
| interleukin 6 signal transducer | ENSG00000134352 | IL6ST | chr5:55935095-55994993:- | 0.06 | 1 |
| fibronectin leucine rich transmembrane protein 3 | ENSG00000125848 | FLRT3 | chr20:14322988-14337616:- | 0.05 | 2 |
| erbb2 interacting protein | ENSG00000112851 | ERBB2IP | chr5:65926475-66082549:+ | 0.05 | 1 |
| protein tyrosine phosphatase receptor type U | ENSG00000060656 | PTPRU | chr1:29236516-29326813:+ | 0.05 | 1 |
| interleukin 4 receptor | ENSG00000077238 | IL4R | chr16:27313668-27364778:+ | 0.05 | 1 |
| erythrocyte membrane protein band 4.1 | ENSG00000159023 | EPB41 | chr1:28887091-29120046:+ | 0.05 | 1 |
| bone morphogenetic protein receptor type 2 | ENSG00000204217 | BMPR2 | chr2:202376936-202567751:+ | 0.05 | 1 |
| insulin receptor substrate 1 | ENSG00000169047 | IRS1 | chr2:226731317-226799759:- | 0.05 | 1 |
| integrin subunit beta 2 | ENSG00000160255 | ITGB2 | chr21:44885953-44931989:- | 0.05 | 1 |
| repulsive guidance molecule BMP co-receptor b | ENSG00000174136 | RGMB | chr5:98768650-98798643:+ | 0.05 | 1 |
| slingshot protein phosphatase 1 | ENSG00000084112 | SSH1 | chr12:108778192-108857590:- | 0.04 | 1 |
| scribble planar cell polarity protein | ENSG00000180900 | SCRIB | chr8:143790920-143815379:- | 0.04 | 1 |
| heat shock protein 90 alpha family class A member 1 | ENSG00000080824 | HSP90AA1 | chr14:102080738-102139699:- | 0.04 | 2 |
| myosin light chain kinase | ENSG00000065534 | MYLK | chr3:123610049-123884331:- | 0.04 | 1 |
| WW domain containing E3 ubiquitin protein ligase 1 | ENSG00000123124 | WWP1 | chr8:86342738-86478420:+ | 0.04 | 1 |
| erythrocyte membrane protein band 4.1 like 2 | ENSG00000079819 | EPB41L2 | chr6:130839347-131063322:- | 0.04 | 1 |
| ATP binding cassette subfamily C member 1 | ENSG00000103222 | ABCC1 | chr16:15949577-16143074:+ | 0.04 | 1 |
| semaphorin 6A | ENSG00000092421 | SEMA6A | chr5:116443616-116574934:- | 0.04 | 1 |
|
Showing page 5 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.