Mutation
The putative cancer-causing HAMPs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| HDAC10 | ENSG00000100429 | 0 | 0 |
| HDAC6 | ENSG00000094631 | 0 | 0 |
| HDAC7 | ENSG00000061273 | 0 | 0 |
| HDAC4 | ENSG00000068024 | 0 | 0 |
| HDAC5 | ENSG00000108840 | 0 | 0 |
| HDAC9 | ENSG00000048052 | 0.26 | 1 |
| SIRT6 | ENSG00000077463 | 0 | 0 |
| SIRT3 | ENSG00000142082 | 0 | 0 |
| SIRT1 | ENSG00000096717 | 0.1 | 1 |
| SIRT2 | ENSG00000068903 | 0 | 0 |
| SIRT7 | ENSG00000187531 | 0 | 0 |
| SIRT4 | ENSG00000089163 | 0 | 0 |
| SIRT5 | ENSG00000124523 | 0 | 0 |
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