Mutation

 

The putative cancer-causing HAMPs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

Pan-cancer level overall M-score of HAMPs


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 HGNC Symbol  Ensembl Gene ID  Overall_Mscore  No. of Cancer Types 
KAT6A  ENSG00000083168    0    0  
KAT6B  ENSG00000156650    0    0  
KAT7  ENSG00000136504    0.32    3  
KAT5  ENSG00000172977    0    0  
KAT8  ENSG00000103510    0.05    1  
CLOCK  ENSG00000134852    0    0  
HAT1  ENSG00000128708    0    0  
ELP3  ENSG00000134014    0.1    1  
KAT2A  ENSG00000108773    0    0  
KAT2B  ENSG00000114166    0.2    1  
TAF1  ENSG00000147133    0.52    2  
TAF1L  ENSG00000122728    0    0  
ATAT1  ENSG00000137343    0    0  
CREBBP  ENSG00000005339    0.91    4  
EP300  ENSG00000100393    1.95    7  
GTF3C4  ENSG00000125484    0    0  
NCOA1  ENSG00000084676    0    0  
NCOA3  ENSG00000124151    0    0  
SP140  ENSG00000079263    0    0  
SP140L  ENSG00000185404    0.02    1  

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