Mutation
The putative cancer-causing HAMPs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| SP100 | ENSG00000067066 | 0.21 | 2 |
| SP110 | ENSG00000135899 | 0 | 0 |
| TRIM28 | ENSG00000130726 | 0 | 0 |
| TRIM33 | ENSG00000197323 | 0.15 | 1 |
| TRIM24 | ENSG00000122779 | 0 | 0 |
| TRIM66 | ENSG00000166436 | 0 | 0 |
| BAZ1A | ENSG00000198604 | 0.06 | 1 |
| SMARCA2 | ENSG00000080503 | 0.31 | 2 |
| SMARCA4 | ENSG00000127616 | 0.52 | 5 |
| ASH1L | ENSG00000116539 | 0.46 | 2 |
| BAZ1B | ENSG00000009954 | 0.06 | 1 |
| PBRM1 | ENSG00000163939 | 1.42 | 4 |
| ZMYND8 | ENSG00000101040 | 0 | 0 |
| ZMYND11 | ENSG00000015171 | 0 | 0 |
| BRD4 | ENSG00000141867 | 0.06 | 1 |
| BPTF | ENSG00000171634 | 0.41 | 3 |
| BRD2 | ENSG00000204256 | 0.09 | 1 |
| BRDT | ENSG00000137948 | 0 | 0 |
| BRD3 | ENSG00000169925 | 0 | 0 |
| KMT2A | ENSG00000118058 | 0.73 | 3 |
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