Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SPOCK1ENSG00000152377                                                                                                                                    
KLHL3ENSG00000146021                                                                                                                                    
CDC25CENSG00000158402                                                                                                                                    
IGIPENSG00000182700                                                                                                                                    
FGF1ENSG00000113578                                                                                                                                    
GPX3ENSG00000211445                                                                                                                                    
ITKENSG00000113263                                                                  1                                                                  
FABP6ENSG00000170231                                                                                                                                    
SERPINB1ENSG00000021355                                                                                                                                    
SERPINB9ENSG00000170542                                                                                                                                    
BPHLENSG00000137274                                                                                                                                    
RIOK1ENSG00000124784                                                                                                                                    
NUP153ENSG00000124789                                                                                                          1                          
TPMTENSG00000137364                                                                                                                                    
TDP2ENSG00000111802                                                                                                                                    
GMNNENSG00000112312                                                                                                                                    
SCGNENSG00000079689                                                                                                                                    
HIST1H3AENSG00000275714                                                                                                                                    
HIST1H4BENSG00000278705                                                                                                                                    
HIST1H3BENSG00000274267                                                                                                                                    

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