Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PRSS1ENSG00000204983                                                                                                                                    
GSTK1ENSG00000197448                                                                                                                                    
DEFB1ENSG00000164825                                                                                                                                    
DEFA5ENSG00000164816                                                                                                                                    
PRSS55ENSG00000184647                                                                                                                                    
NAT1ENSG00000171428                                                                                                                                    
EPHX2ENSG00000120915                                                                                                                                    
DUSP26ENSG00000133878                                                                                                                                    
IKBKBENSG00000104365                                                                                                                                    
SGK3ENSG00000104205                                                                                                                                    
IMPA1ENSG00000133731                                                                                                                                    
GDF6ENSG00000156466                                                                                                                                    
FREM1ENSG00000164946                                                                                                                                    
IFNA6ENSG00000120235                                                                                                                                    
ALDH1B1ENSG00000137124                                                                                                                                    
PRKACGENSG00000165059                                                                                                                                    
PTPDC1ENSG00000158079                                                                                                                                    
FBP1ENSG00000165140                                                                                                                                    
PTGR1ENSG00000106853                                                                                                                                    
NEK6ENSG00000119408                                                                                                                                    

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