Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
ATMENSG00000149311      1                1                                            1                        1    1                            1          
SIK2ENSG00000170145                                                                                                                                    
SIK3ENSG00000160584                                                                                                                                    
HSD17B6ENSG00000025423                                                                                                                                    
TBK1ENSG00000183735                                                                      1                                                    1          
CITENSG00000122966                                                                                                                                    
CAMKK2ENSG00000110931                                                                                                                                    
COL4A2ENSG00000134871                                                                                                                                    
EDDM3AENSG00000181562                                                                                                                                    
RNASE7ENSG00000165799                                                                                                                                    
ALDH6A1ENSG00000119711                                                                                                      1                              
NEK9ENSG00000119638                                                                                                                                    
HERC1ENSG00000103657                                      1                                                                                              
DAPK2ENSG00000035664                                                                                                                                    
ADAMTS17ENSG00000140470                                                                                                                                    
XYLT1ENSG00000103489                                                                                                                                    
SMG1ENSG00000157106                                                                                                                                    
SBK1ENSG00000188322                                                                                                                                    
MYLK3ENSG00000140795                                                                                                                                    
MMP2ENSG00000087245                                                                  1                                                                  

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