Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PEBP1ENSG00000089220                                                                                                                                    
TAOK3ENSG00000135090                                                                                                                                    
SMOC1ENSG00000198732                                                                                                                                    
PTPN21ENSG00000070778                                                                                                                                    
TDP1ENSG00000042088                                                                      1                                                              
IGHV1-2ENSG00000211934                                                                                                                                    
IGHV3-23ENSG00000211949                                                                                                                                    
IGHV1-46ENSG00000211962                                                                                                                                    
MLKLENSG00000168404                                                                                                                                    
KARSENSG00000065427                                                                                                                                    
PLCG2ENSG00000197943                                                                                                                                    
TNK1ENSG00000174292                                                                                                                                    
ALOXE3ENSG00000179148                                                                                                                                    
MAP2K4ENSG00000065559          1            1                                                                                                              
CDK5R1ENSG00000176749                                                                                                                                    
PIP4K2BENSG00000276293                                                                                                                                    
CACNB1ENSG00000067191                                                                                                                                    
TEX14ENSG00000121101                                                                                                                                    
PRKAR1AENSG00000108946  1                                                                                                                                  
SERPINB3ENSG00000057149                                                                                                                                    

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