Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
MAP4K5ENSG00000012983                                                                                                                                    
PYGLENSG00000100504                                                                                                      1                              
OR5L1ENSG00000279395                                                                                                                                    
SERPINA6ENSG00000170099                                                                                                                                    
SERPINA11ENSG00000186910                                                                                                                                    
GREM1ENSG00000166923                                                                                                                                    
FGF7ENSG00000140285                                                                                                                                    
HEXAENSG00000213614                                                                                                                                    
CTSHENSG00000103811                                                                                                                                    
IL16ENSG00000172349                                                                  1                                                                  
OR5AK3PENSG00000181282                                                                                                                                    
PRSS27ENSG00000172382                                                                                                                                    
OR10D4PENSG00000186268                                                                                                                                    
OR8D2ENSG00000279116                                                                                                                                    
CES4AENSG00000172824                                                                                                                                    
CTRLENSG00000141086                                                                                                                                    
SERPINF1ENSG00000132386                                                                                                                          1          
MFAP4ENSG00000166482                                                                                                                                    
CCL14ENSG00000276409                                                                                                                                    
FKBP10ENSG00000141756                                                                                                                                    

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