Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 258 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| AMY1B | ENSG00000174876 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| AMY1C | ENSG00000187733 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.97 | 0.00 | 0.00 | 0.77 | 0.40 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 1.11 | 0.38 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 1.82 | 0.00 |
| PSMA5 | ENSG00000143106 | 0.00 | 0.76 | 0.21 | 0.00 | 2.86 | 0.32 | 0.00 | 0.55 | 0.26 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.00 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.83 | 0.00 | 0.00 | 0.00 |
| GSTM4 | ENSG00000168765 | 0.00 | 0.00 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| GSTM2 | ENSG00000213366 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.24 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| GSTM1 | ENSG00000134184 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| GSTM3 | ENSG00000134202 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.38 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| AMPD1 | ENSG00000116748 | 0.00 | 1.53 | 0.52 | 1.46 | 2.86 | 1.29 | 0.00 | 1.10 | 1.55 | 1.20 | 1.54 | 0.54 | 0.00 | 0.00 | 0.59 | 1.11 | 3.20 | 1.50 | 0.00 | 1.47 | 2.30 | 0.00 | 0.41 | 1.56 | 0.43 | 5.69 | 1.08 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| CASQ2 | ENSG00000118729 | 0.00 | 1.27 | 0.62 | 0.36 | 0.00 | 0.65 | 0.00 | 0.00 | 0.26 | 0.60 | 0.00 | 0.54 | 0.00 | 0.00 | 0.20 | 0.00 | 0.75 | 1.07 | 0.00 | 0.49 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| HMGCS2 | ENSG00000134240 | 1.11 | 1.53 | 0.10 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.40 | 0.00 | 0.54 | 0.71 | 0.00 | 0.20 | 0.28 | 0.56 | 0.86 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 2.84 | 0.00 | 0.00 | 0.00 | 0.00 | 0.89 | 1.82 | 0.00 |
| DRD5P2 | ENSG00000175658 | |||||||||||||||||||||||||||||||||
| PRKAB2 | ENSG00000131791 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.00 | 0.43 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| ACP6 | ENSG00000162836 | 0.00 | 0.00 | 0.31 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.52 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.64 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.42 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| PPIAL4C | ENSG00000263464 | |||||||||||||||||||||||||||||||||
| HIST2H3A | ENSG00000203852 | |||||||||||||||||||||||||||||||||
| ARNT | ENSG00000143437 | 0.00 | 2.54 | 0.41 | 0.36 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 1.39 | 0.00 | 0.27 | 0.00 | 0.74 | 0.20 | 0.00 | 0.75 | 0.64 | 0.00 | 0.49 | 0.00 | 1.12 | 0.20 | 0.00 | 0.00 | 1.66 | 0.27 | 0.69 | 0.00 | 0.00 | 1.77 | 0.00 | 0.00 |
| PSMB4 | ENSG00000159377 | 0.00 | 0.25 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.86 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| TUFT1 | ENSG00000143367 | 0.00 | 1.02 | 0.21 | 0.36 | 2.86 | 0.32 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.38 | 0.00 | 1.23 | 0.25 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| RORC | ENSG00000143365 | 1.11 | 1.27 | 0.31 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 1.03 | 0.00 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.00 | 0.19 | 1.29 | 1.23 | 0.74 | 0.57 | 0.56 | 0.00 | 0.78 | 0.43 | 2.37 | 0.54 | 0.00 | 0.00 | 0.00 | 1.55 | 0.00 | 0.00 |
| RPTN | ENSG00000215853 | 2.22 | 1.53 | 0.93 | 0.73 | 0.00 | 0.32 | 5.41 | 0.55 | 0.77 | 1.00 | 0.00 | 0.54 | 1.42 | 0.74 | 0.00 | 0.56 | 2.64 | 2.58 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.78 | 0.86 | 10.19 | 1.36 | 0.00 | 0.20 | 0.00 | 2.22 | 1.82 | 0.00 |
|
Showing page 258 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.