Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 198 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| TUBB3 | ENSG00000198211 | |||||||||||||||||||||||||||||||||
| DHRS7C | ENSG00000184544 | 0.00 | 0.51 | 0.31 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 1.00 | 0.00 | 0.54 | 0.36 | 0.00 | 0.20 | 0.00 | 0.94 | 1.72 | 0.00 | 0.00 | 0.00 | 0.00 | 0.41 | 2.34 | 0.00 | 2.37 | 0.54 | 0.69 | 0.00 | 0.00 | 0.44 | 1.82 | 0.00 |
| G6PC | ENSG00000131482 | 0.00 | 0.00 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.40 | 0.00 | 0.81 | 0.00 | 0.00 | 0.59 | 0.83 | 1.32 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.90 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| PCSK4 | ENSG00000115257 | 1.11 | 0.51 | 0.10 | 1.82 | 0.00 | 0.65 | 0.00 | 0.55 | 0.26 | 0.20 | 0.00 | 0.00 | 0.71 | 0.00 | 0.39 | 0.83 | 1.13 | 0.64 | 0.00 | 0.00 | 0.00 | 0.56 | 0.41 | 0.78 | 0.00 | 1.18 | 0.54 | 0.69 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| CYP4F12 | ENSG00000186204 | 0.00 | 1.27 | 0.21 | 0.36 | 0.00 | 0.97 | 0.00 | 0.00 | 0.77 | 1.00 | 0.00 | 0.54 | 0.00 | 0.00 | 0.39 | 0.00 | 2.26 | 1.93 | 0.00 | 0.98 | 0.00 | 0.00 | 0.41 | 0.78 | 0.00 | 5.21 | 0.81 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| SLC35E1 | ENSG00000127526 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.74 | 0.00 | 1.11 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| CYP2S1 | ENSG00000167600 | 0.00 | 0.76 | 0.41 | 0.00 | 2.86 | 0.65 | 0.00 | 0.55 | 0.26 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.28 | 0.56 | 0.00 | 1.23 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 3.08 | 1.08 | 0.00 | 0.00 | 0.00 | 1.55 | 1.82 | 0.00 |
| EMC10 | ENSG00000161671 | 0.00 | 0.25 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.56 | 0.19 | 0.00 | 1.23 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| SLC27A5 | ENSG00000083807 | 1.11 | 2.04 | 0.21 | 2.92 | 0.00 | 0.97 | 2.70 | 0.55 | 0.00 | 0.40 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.00 | 0.75 | 1.29 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 3.32 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| SRD5A2 | ENSG00000277893 | |||||||||||||||||||||||||||||||||
| CYP1B1 | ENSG00000138061 | 0.00 | 0.76 | 0.21 | 0.36 | 0.00 | 0.97 | 0.00 | 0.00 | 0.52 | 0.80 | 0.00 | 0.54 | 0.71 | 0.00 | 0.00 | 0.56 | 0.75 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| CNGA3 | ENSG00000144191 | 0.00 | 1.02 | 0.41 | 0.36 | 0.00 | 1.29 | 0.00 | 1.10 | 0.00 | 1.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.39 | 3.33 | 1.69 | 2.36 | 0.00 | 1.72 | 1.72 | 0.00 | 0.20 | 1.56 | 1.29 | 4.03 | 1.36 | 0.00 | 0.00 | 0.00 | 1.33 | 1.82 | 0.00 |
| DHRS9 | ENSG00000073737 | 1.11 | 1.27 | 0.31 | 0.73 | 0.00 | 0.00 | 0.00 | 0.55 | 0.26 | 0.80 | 0.00 | 0.00 | 1.07 | 0.00 | 0.20 | 0.56 | 0.56 | 0.86 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 1.90 | 0.81 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| DNAJC10 | ENSG00000077232 | 0.00 | 1.53 | 0.41 | 0.36 | 0.00 | 0.97 | 2.70 | 0.00 | 0.52 | 1.00 | 0.00 | 1.36 | 0.00 | 0.74 | 0.20 | 0.00 | 2.07 | 1.93 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 1.90 | 0.54 | 0.00 | 0.00 | 0.00 | 1.77 | 0.00 | 0.00 |
| FKBP1A | ENSG00000088832 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| TUBA8 | ENSG00000183785 | 1.11 | 0.00 | 0.21 | 0.73 | 0.00 | 0.00 | 0.00 | 1.10 | 0.26 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.56 | 0.19 | 0.43 | 0.00 | 0.49 | 0.57 | 0.56 | 0.00 | 0.00 | 0.00 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| SLC35E4 | ENSG00000100036 | 0.00 | 1.02 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.38 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| C1QTNF6 | ENSG00000133466 | 0.00 | 0.00 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.27 | 0.71 | 0.00 | 0.20 | 0.00 | 0.00 | 0.86 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| PLA2G6 | ENSG00000184381 | 0.00 | 0.76 | 0.62 | 0.36 | 0.00 | 0.00 | 0.00 | 1.10 | 0.26 | 0.40 | 0.00 | 0.54 | 0.71 | 0.00 | 0.00 | 0.56 | 0.38 | 1.07 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 1.90 | 0.27 | 0.00 | 0.20 | 0.00 | 2.00 | 0.00 | 1.25 |
| CPT1B | ENSG00000205560 | 0.00 | 1.02 | 0.10 | 0.73 | 0.00 | 0.32 | 0.00 | 1.66 | 0.26 | 0.80 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 0.75 | 0.64 | 0.00 | 1.47 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 1.42 | 0.00 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
|
Showing page 198 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.