PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 15  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
fibrillarinENSG00000105202FBLchr19:39834458-39846414:-Tbio75.8015
retinoid X receptor alphaENSG00000186350RXRAchr9:134317098-134440585:+Tclin1398.44
keratin 8ENSG00000170421KRT8chr12:52897187-52949954:-Tbio543.348
chitinase 3 like 1ENSG00000133048CHI3L1chr1:203178931-203186749:-Tbio667.027
valosin containing proteinENSG00000165280VCPchr9:35056064-35073249:-Tchem506.2
fibroblast activation protein alphaENSG00000078098FAPchr2:162170684-162245151:-Tchem261.857
protein kinase, membrane associated tyrosine/threonine 1ENSG00000127564PKMYT1chr16:2968024-2980539:-Tchem13.5335
protein kinase C alphaENSG00000154229PRKCAchr17:66302636-66810743:+Tchem1382.62
integrin subunit alpha VENSG00000138448ITGAVchr2:186590065-186680901:+Tchem468.153
cytochrome P450 family 2 subfamily D member 6ENSG00000100197CYP2D6chr22:42126499-42130906:-Tclin3522.58
interleukin 1 alphaENSG00000115008IL1Achr2:112773915-112784590:-Tchem6881.77
angiopoietin 2ENSG00000091879ANGPT2chr8:6499651-6563409:-Tbio678.574
stanniocalcin 1ENSG00000159167STC1chr8:23841915-23854807:-Tbio255.892
VGF nerve growth factor inducibleENSG00000128564VGFchr7:101162509-101165593:-Tbio69.2742
lysine acetyltransferase 6AENSG00000083168KAT6Achr8:41929479-42051990:-Tbio62.3627
solute carrier family 16 member 3ENSG00000141526SLC16A3chr17:82228397-82261129:+Tchem76.7627
thrombospondin 2ENSG00000186340THBS2chr6:169215780-169254044:-Tbio130.127
elongator acetyltransferase complex subunit 3ENSG00000134014ELP3chr8:28089673-28191156:+Tbio19.7119
tryptophanyl-tRNA synthetase 1ENSG00000140105WARSchr14:100333788-100376805:-Tbio649.79
low density lipoprotein receptorENSG00000130164LDLRchr19:11089362-11133816:+Tchem4075.98

 Showing page 15  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.