Gene

 

Histone acetylation modulator proteins (HAMPs), the primary protein families that mediate the modification and recognition of histone acetylation, include histone acetyltransferases (HATs; “writers”), histone deacetylases (HDACs; “erasers”), and proteins containing bromodomains (BRD-containing proteins or acetyl-Lys-binding proteins; “readers”).

 

List of the HAMPs in the human genome


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NameHGNC SymbolProtein GroupsEnsembl Gene IDGenomic Location
Histone deacetylase 10HDAC10EraserENSG0000010042922:50245183-50251405
Histone deacetylase 6HDAC6EraserENSG00000094631X:48801377-48824982
Histone deacetylase 7HDAC7EraserENSG0000006127312:47782722-47833132
Histone deacetylase 4HDAC4EraserENSG000000680242:239048168-239401654
Histone deacetylase 5HDAC5EraserENSG0000010884017:44076746-44123702
Histone deacetylase 9HDAC9EraserENSG000000480527:18086949-19002416
Sirtuin 6SIRT6EraserENSG0000007746319:4174109-4182604
Sirtuin 3SIRT3EraserENSG0000014208211:215458-236931
Sirtuin 1SIRT1EraserENSG0000009671710:67884669-67918390
Sirtuin 2SIRT2EraserENSG0000006890319:38878555-38899862
Sirtuin 7SIRT7EraserENSG0000018753117:81911939-81921323
Sirtuin 4SIRT4EraserENSG0000008916312:120302316-120313249
Sirtuin 5SIRT5EraserENSG000001245236:13574529-13615158

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