SRMS
Official symbol: | SRMS |
Full name: | src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites |
Location: | 20q13.33 |
Also known as: | PTK70, SRM, dJ697K14.1, C20orf148 |
Entrez ID: | 6725 |
Ensembl ID: | ENSG00000125508 |
Summary: | |
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Overall distribution
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Tissue specific distribution
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Expression restricted in 3 cancer type(s) | Cancer specific in breast cancer subtype (ER; Her2; LumA; LumB) |
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Overall distribution
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Tissue specific distribution
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Gscore (Amp): | 0.32 | Gscore (Del): | 0.00 |
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Recurrently amplified in 1 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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Overall
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Tissue specific
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Total fusion occurrence: | NA |
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Functional class: | Kinase (protein kinase) |
JensenLab PubMed score: | 23.05 (Percentile rank: 49.70%) |
PubTator score: | 2.83 (Percentile rank: 21.20%) |
Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
Tractability (small molecule): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
Tractability (antibody): | |