PDPK1
Official symbol: | PDPK1 |
Full name: | 3-phosphoinositide dependent protein kinase 1 |
Location: | 16p13.3 |
Also known as: | PDK1 |
Entrez ID: | 5170 |
Ensembl ID: | ENSG00000140992 |
Summary: | |
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Overall distribution
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Tissue specific distribution
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Overall distribution
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Tissue specific distribution
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Gscore (Amp): | 0.00 | Gscore (Del): | 0.00 |
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Overall distribution
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Tissue specific distribution
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Tissue specific
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Total fusion occurrence: | 2 |
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Fusions detected in 2 cancer type(s) |
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Tissue specific
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CRISPR: COMMON ESSENTIAL |
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Functional class: | Kinase (protein kinase) |
JensenLab PubMed score: | 204.92 (Percentile rank: 82.01%) |
PubTator score: | 53.11 (Percentile rank: 68.93%) |
Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
Tractability (small molecule): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |