MELK
| Official symbol: | MELK |
| Full name: | maternal embryonic leucine zipper kinase |
| Location: | 9p13.2 |
| Also known as: | KIAA0175 |
| Entrez ID: | 9833 |
| Ensembl ID: | ENSG00000165304 |
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Overall distribution
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Tissue specific distribution
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| Expression restricted in 17 cancer type(s) | | Cancer specific in breast cancer subtype (Basal; Her2; LumB; T) |
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Overall distribution
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Tissue specific distribution
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| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.11 |
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| Recurrently deleted in 1 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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Overall
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Tissue specific
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| Total fusion occurrence: | 5 |
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| Fusions detected in 4 cancer type(s) |
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| Functional class: | Kinase (protein kinase) |
| JensenLab PubMed score: | 88.41 (Percentile rank: 70.91%) |
| PubTator score: | 54.97 (Percentile rank: 69.49%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
