MAP4K1
| Official symbol: | MAP4K1 |
| Full name: | mitogen-activated protein kinase kinase kinase kinase 1 |
| Location: | 19q13.2 |
| Also known as: | HPK1 |
| Entrez ID: | 11184 |
| Ensembl ID: | ENSG00000104814 |
| Summary: | |
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Overall distribution
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Tissue specific distribution
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| Expression restricted in 1 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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| Gscore (Amp): | 0.54 | | Gscore (Del): | 0.00 |
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| Recurrently amplified in 1 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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Overall
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Tissue specific
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| Total fusion occurrence: | 3 |
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| Fusions detected in 3 cancer type(s) |
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| Functional class: | Kinase (protein kinase) |
| JensenLab PubMed score: | 32.28 (Percentile rank: 55.18%) |
| PubTator score: | 38.25 (Percentile rank: 63.51%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | |