Transcript Fusion
The transcript fusion data of TCGA were retrieved from the TumorFusions database.
List of the transcript fusions of the PDGs in each cancer type
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Cancer Type | TCGA_barcode | Patient | Fusion_transcript | Gene_A | Gene_B | Chr_A | Chr_B | Strand_A | Strand_B | #_Discordant_Pairs | #_JSR | #_perfect_JSR | Evalue | Junction_A | Junction_B | Tier | Frame | TN | WGS_validation | Centrality |
LUAD | TCGA-44-5644-01A | TCGA-44-5644 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 17 | 9 | 9 | 0.79 | 104707254 | 104546634 | tier1 | Out-of-frame | 10484 | NA | 0.34946 |
LUAD | TCGA-55-7727-01A | TCGA-55-7727 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 13 | 8 | 7 | 0.79 | 104722244 | 104546634 | tier1 | Out-of-frame | 10485 | NA | 0.34946 |
OV | TCGA-24-0970-01B | TCGA-24-0970 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 18 | 13 | 13 | 0.79 | 104654982 | 104546634 | tier1 | 5UTR-CDS | 10483 | NA | 0.34946 |
SKCM | TCGA-EB-A3Y6-01A | TCGA-EB-A3Y6 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 4 | 2 | 2 | 0.79 | 104681470 | 104546634 | tier1 | Out-of-frame | 10493 | NA | 0.34946 |
STAD | TCGA-CD-8535-01A | TCGA-CD-8535 | MLL5|KIAA1267 | MLL5 | KIAA1267 | 7 | 17 | 1 | -1 | 4 | 42 | 37 | 0.38 | 104681470 | 44249598 | tier1 | CDS-5UTR | 10482 | NA | 0.36009 |
STAD | TCGA-BR-4357-01A | TCGA-BR-4357 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 13 | 24 | 22 | 0.79 | 104654982 | 104546634 | tier1 | 5UTR-CDS | 10489 | NA | 0.34946 |
STAD | TCGA-BR-8289-01A | TCGA-BR-8289 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 4 | 17 | 17 | 0.79 | 104707254 | 104546634 | tier1 | Out-of-frame | 10490 | NA | 0.34946 |
STAD | TCGA-BR-8373-01A | TCGA-BR-8373 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 5 | 25 | 24 | 0.79 | 104681470 | 104546634 | tier1 | Out-of-frame | 10491 | non-validated | 0.34946 |
STAD | TCGA-VQ-A925-01A | TCGA-VQ-A925 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 2 | 43 | 37 | 0.79 | 104654982 | 104377122 | tier2 | 5UTR-CDS | 10496 | NA | 0.34946 |
STAD | TCGA-BR-4357-01A | TCGA-BR-4357 | MLL5|RAPGEF1 | MLL5 | RAPGEF1 | 7 | 9 | 1 | -1 | 8 | 5 | 5 | 1.7 | 104722244 | 134479440 | tier1 | NA | 10499 | NA | 0.37319 |
UCEC | TCGA-A5-A7WK-01A | TCGA-A5-A7WK | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 96 | 122 | 108 | 0.79 | 104654982 | 104546634 | tier1 | 5UTR-CDS | 10486 | NA | 0.34946 |
UCEC | TCGA-AX-A2H4-01A | TCGA-AX-A2H4 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 10 | 5 | 4 | 0.79 | 104717880 | 104377122 | tier1 | Out-of-frame | 10487 | NA | 0.34946 |
UCS | TCGA-NA-A4R1-01A | TCGA-NA-A4R1 | MLL5|LHFPL3 | MLL5 | LHFPL3 | 7 | 7 | 1 | 1 | 269 | 54 | 39 | 0.79 | 104730720 | 104377122 | tier1 | Out-of-frame | 10495 | NA | 0.34946 |
BRCA | TCGA-AR-A250-01A | TCGA-AR-A250 | PDK2|CDK12 | PDK2 | CDK12 | 17 | 17 | 1 | 1 | 24 | 26 | 24 | 1 | 48182806 | 37627132 | tier1 | In-frame | 12548 | NA | 0.36144 |
KIRP | TCGA-G7-6793-01A | TCGA-G7-6793 | ITGA3|EIF2AK2 | ITGA3 | EIF2AK2 | 17 | 2 | 1 | -1 | 2 | 4 | 3 | 0.5 | 48167848 | 37342384 | tier4 | NA | 8378 | NA | 0.38699 |
CESC | TCGA-C5-A2LV-01A | TCGA-C5-A2LV | ITGA3|NDUFV1 | ITGA3 | NDUFV1 | 17 | 11 | 1 | 1 | 2 | 19 | 18 | 0.079 | 48167844 | 67375697 | tier3 | NA | 8379 | non-validated | 0.36397 |
LUAD | TCGA-44-3396-01A | TCGA-44-3396 | ITGA3|C17orf37 | ITGA3 | C17orf37 | 17 | 17 | 1 | -1 | 119 | 100 | 83 | 0.6 | 48134009 | 37886544 | tier1 | In-frame | 8377 | NA | 0 |
CESC | TCGA-C5-A2LX-01A | TCGA-C5-A2LX | MAP3K14|ACBD4 | MAP3K14 | ACBD4 | 17 | 17 | -1 | 1 | 2 | 1 | 1 | 0.026 | 43362179 | 43219950 | tier2 | Out-of-frame | 9861 | NA | 0.37564 |
CESC | TCGA-R2-A69V-01A | TCGA-R2-A69V | MAP3K14|NDEL1 | MAP3K14 | NDEL1 | 17 | 17 | -1 | 1 | 3 | 2 | 2 | 1.3 | 43366602 | 8370248 | tier1 | In-frame | 9862 | NA | 0.37756 |
SARC | TCGA-X6-A7W8-01A | TCGA-X6-A7W8 | MAP3K14|SRP68 | MAP3K14 | SRP68 | 17 | 17 | -1 | -1 | 2 | 5 | 5 | 0.4 | 43362179 | 74063411 | tier2 | Out-of-frame | 9863 | NA | 0.37386 |
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