Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| GPC3 | ENSG00000147257 | 0.00 | 0 |
| SLC6A8 | ENSG00000130821 | 0.00 | 0 |
| CEACAM8 | ENSG00000124469 | 0.00 | 0 |
| ALPPL2 | ENSG00000163286 | 0.00 | 0 |
| SLIT2 | ENSG00000145147 | 0.00 | 0 |
| ALPI | ENSG00000163295 | 0.00 | 0 |
| PLAU | ENSG00000122861 | 0.00 | 0 |
| SLIT3 | ENSG00000184347 | 0.00 | 0 |
| SEMA3C | ENSG00000075223 | 0.00 | 0 |
| LAMC1 | ENSG00000135862 | 0.00 | 0 |
| COL6A2 | ENSG00000142173 | 0.00 | 0 |
| FGA | ENSG00000171560 | 0.00 | 0 |
| THBS2 | ENSG00000186340 | 0.00 | 0 |
| C5AR1 | ENSG00000197405 | 0.00 | 0 |
| TACR1 | ENSG00000115353 | 0.00 | 0 |
| P2RY1 | ENSG00000169860 | 0.00 | 0 |
| CHRM4 | ENSG00000180720 | 0.00 | 0 |
| CCR2 | ENSG00000121807 | 0.00 | 0 |
| CCKAR | ENSG00000163394 | 0.00 | 0 |
| CNR1 | ENSG00000118432 | 0.00 | 0 |
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