Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| APP | ENSG00000142192 | 0.00 | 0 |
| EPHA1 | ENSG00000146904 | 0.00 | 0 |
| EPHA7 | ENSG00000135333 | 0.00 | 0 |
| LILRB2 | ENSG00000131042 | 0.00 | 0 |
| ITGAV | ENSG00000138448 | 0.00 | 0 |
| SLC6A9 | ENSG00000196517 | 0.00 | 0 |
| ANTXR2 | ENSG00000163297 | 0.00 | 0 |
| TRPV2 | ENSG00000187688 | 0.00 | 0 |
| PTK7 | ENSG00000112655 | 0.00 | 0 |
| SLC38A1 | ENSG00000111371 | 0.00 | 0 |
| LRP1 | ENSG00000123384 | 0.00 | 0 |
| RIPK1 | ENSG00000137275 | 0.00 | 0 |
| HLA-DRA | ENSG00000204287 | 0.00 | 0 |
| ACE | ENSG00000159640 | 0.00 | 0 |
| SLC2A3 | ENSG00000059804 | 0.00 | 0 |
| ITGB1 | ENSG00000150093 | 0.07 | 1 |
| IL1R1 | ENSG00000115594 | 0.00 | 0 |
| PRKCH | ENSG00000027075 | 0.00 | 0 |
| KCNK10 | ENSG00000100433 | 0.00 | 0 |
| FES | ENSG00000182511 | 0.00 | 0 |
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