Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| PRF1 | ENSG00000180644 | 0.00 | 0 |
| PLA2G3 | ENSG00000100078 | 0.00 | 0 |
| AMBP | ENSG00000106927 | 0.00 | 0 |
| GCGR | ENSG00000215644 | 0.00 | 0 |
| HTR1B | ENSG00000135312 | 0.00 | 0 |
| CNR2 | ENSG00000188822 | 0.00 | 0 |
| LPAR3 | ENSG00000171517 | 0.00 | 0 |
| CHRM3 | ENSG00000133019 | 0.00 | 0 |
| GPR158 | ENSG00000151025 | 0.00 | 0 |
| ADRA2A | ENSG00000150594 | 0.00 | 0 |
| C3AR1 | ENSG00000171860 | 0.00 | 0 |
| HCAR3 | ENSG00000255398 | 0.00 | 0 |
| KISS1R | ENSG00000116014 | 0.00 | 0 |
| DRD5 | ENSG00000169676 | 0.00 | 0 |
| CLCN1 | ENSG00000188037 | 0.00 | 0 |
| CSF3R | ENSG00000119535 | 0.00 | 0 |
| LGR6 | ENSG00000133067 | 0.00 | 0 |
| SCN2B | ENSG00000149575 | 0.00 | 0 |
| SLCO1B3 | ENSG00000111700 | 0.00 | 0 |
| GPR176 | ENSG00000166073 | 0.00 | 0 |
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