Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| ARAF | ENSG00000078061 | 0.08 | 2 |
| SUV39H1 | ENSG00000101945 | 0.00 | 0 |
| PHF8 | ENSG00000172943 | 0.00 | 0 |
| MTRNR2L10 | ENSG00000256045 | 0.00 | 0 |
| TAF1 | ENSG00000147133 | 0.44 | 2 |
| KLHL4 | ENSG00000102271 | 0.00 | 0 |
| TEX13A | ENSG00000268629 | 0.00 | 0 |
| MORC4 | ENSG00000133131 | 0.00 | 0 |
| PRPS1 | ENSG00000147224 | 0.00 | 0 |
| ATG4A | ENSG00000101844 | 0.00 | 0 |
| COL4A6 | ENSG00000197565 | 0.00 | 0 |
| KLHL13 | ENSG00000003096 | 0.00 | 0 |
| IKBKG | ENSG00000269335 | 0.00 | 0 |
| AMELY | ENSG00000099721 | 0.00 | 0 |
| PRKY | ENSG00000099725 | 0.00 | 0 |
| INTS12 | ENSG00000138785 | 0.00 | 0 |
| ORC1 | ENSG00000085840 | 0.00 | 0 |
| MPHOSPH8 | ENSG00000196199 | 0.00 | 0 |
| BRPF1 | ENSG00000156983 | 0.00 | 0 |
| CHD9 | ENSG00000177200 | 0.00 | 0 |
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