Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| SERPINB10 | ENSG00000242550 | 0.00 | 0 |
| CNDP1 | ENSG00000150656 | 0.00 | 0 |
| ZADH2 | ENSG00000180011 | 0.00 | 0 |
| DOT1L | ENSG00000104885 | 0.00 | 0 |
| DPP9 | ENSG00000142002 | 0.00 | 0 |
| LONP1 | ENSG00000196365 | 0.00 | 0 |
| NRTN | ENSG00000171119 | 0.00 | 0 |
| CLPP | ENSG00000125656 | 0.00 | 0 |
| RETN | ENSG00000104918 | 0.00 | 0 |
| PIN1 | ENSG00000127445 | 0.00 | 0 |
| DNMT1 | ENSG00000130816 | 0.08 | 1 |
| ACP5 | ENSG00000102575 | 0.00 | 0 |
| RLN3 | ENSG00000171136 | 0.00 | 0 |
| BRD4 | ENSG00000141867 | 0.00 | 0 |
| PDE4C | ENSG00000105650 | 0.00 | 0 |
| CCNE1 | ENSG00000105173 | 0.00 | 0 |
| PEPD | ENSG00000124299 | 0.00 | 0 |
| KRTDAP | ENSG00000188508 | 0.00 | 0 |
| DMKN | ENSG00000161249 | 0.00 | 0 |
| DYRK1B | ENSG00000105204 | 0.00 | 0 |
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