Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| MUCL1 | ENSG00000172551 | 0.00 | 0 |
| MMP19 | ENSG00000123342 | 0.00 | 0 |
| IL23A | ENSG00000110944 | 0.00 | 0 |
| STAT6 | ENSG00000166888 | 0.00 | 0 |
| CDK4 | ENSG00000135446 | 0.09 | 1 |
| USP15 | ENSG00000135655 | 0.00 | 0 |
| IRAK3 | ENSG00000090376 | 0.00 | 0 |
| DUSP6 | ENSG00000139318 | 0.02 | 1 |
| EPYC | ENSG00000083782 | 0.00 | 0 |
| CDK17 | ENSG00000059758 | 0.00 | 0 |
| DAO | ENSG00000110887 | 0.00 | 0 |
| OAS1 | ENSG00000089127 | 0.00 | 0 |
| TRIAP1 | ENSG00000170855 | 0.00 | 0 |
| TUBA3C | ENSG00000198033 | 0.00 | 0 |
| FGF9 | ENSG00000102678 | 0.00 | 0 |
| MIPEP | ENSG00000027001 | 0.00 | 0 |
| C1QTNF9 | ENSG00000240654 | 0.00 | 0 |
| CCNA1 | ENSG00000133101 | 0.00 | 0 |
| CSNK1A1L | ENSG00000180138 | 0.00 | 0 |
| NEK5 | ENSG00000197168 | 0.00 | 0 |
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