Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| CXCL17 | ENSG00000189377 | 0.00 | 0 |
| SAE1 | ENSG00000142230 | 0.00 | 0 |
| HSD17B14 | ENSG00000087076 | 0.00 | 0 |
| KLK6 | ENSG00000167755 | 0.00 | 0 |
| RDH13 | ENSG00000160439 | 0.00 | 0 |
| IL11 | ENSG00000095752 | 0.00 | 0 |
| AURKC | ENSG00000105146 | 0.00 | 0 |
| KHK | ENSG00000138030 | 0.00 | 0 |
| CAD | ENSG00000084774 | 0.08 | 2 |
| REG1B | ENSG00000172023 | 0.00 | 0 |
| REG3A | ENSG00000172016 | 0.00 | 0 |
| MAP4K4 | ENSG00000071054 | 0.00 | 0 |
| BUB1 | ENSG00000169679 | 0.00 | 0 |
| INHBB | ENSG00000163083 | 0.00 | 0 |
| CYP27C1 | ENSG00000186684 | 0.00 | 0 |
| GPD2 | ENSG00000115159 | 0.00 | 0 |
| PDE11A | ENSG00000128655 | 0.00 | 0 |
| CDK15 | ENSG00000138395 | 0.00 | 0 |
| CPS1 | ENSG00000021826 | 0.42 | 2 |
| STK16 | ENSG00000115661 | 0.00 | 0 |
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