Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| CGREF1 | ENSG00000138028 | 0.00 | 0 |
| GKN1 | ENSG00000169605 | 0.00 | 0 |
| GFPT1 | ENSG00000198380 | 0.04 | 1 |
| TTN | ENSG00000155657 | 0.00 | 0 |
| CLK1 | ENSG00000013441 | 0.00 | 0 |
| STRADB | ENSG00000082146 | 0.00 | 0 |
| CYP27A1 | ENSG00000135929 | 0.00 | 0 |
| DNPEP | ENSG00000123992 | 0.00 | 0 |
| SCG2 | ENSG00000171951 | 0.00 | 0 |
| CST9 | ENSG00000173335 | 0.00 | 0 |
| CST3 | ENSG00000101439 | 0.00 | 0 |
| WFDC8 | ENSG00000158901 | 0.00 | 0 |
| CBR1 | ENSG00000159228 | 0.00 | 0 |
| SIK1 | ENSG00000142178 | 0.00 | 0 |
| LSS | ENSG00000160285 | 0.00 | 0 |
| CHEK2 | ENSG00000183765 | 0.00 | 0 |
| INPP5J | ENSG00000185133 | 0.00 | 0 |
| CAMK1 | ENSG00000134072 | 0.00 | 0 |
| NEK10 | ENSG00000163491 | 0.00 | 0 |
| SLC25A38 | ENSG00000144659 | 0.00 | 0 |
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