Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| TRIB2 | ENSG00000071575 | 0.00 | 0 |
| CYP26B1 | ENSG00000003137 | 0.00 | 0 |
| PPIL3 | ENSG00000240344 | 0.00 | 0 |
| ADAMTS1 | ENSG00000154734 | 0.00 | 0 |
| APOL1 | ENSG00000100342 | 0.00 | 0 |
| CYB5R3 | ENSG00000100243 | 0.00 | 0 |
| FAM19A5 | ENSG00000219438 | 0.00 | 0 |
| DCLK3 | ENSG00000163673 | 0.00 | 0 |
| ULK4 | ENSG00000168038 | 0.00 | 0 |
| SLC25A26 | ENSG00000144741 | 0.00 | 0 |
| TERT | ENSG00000164362 | 0.00 | 0 |
| CRISP3 | ENSG00000096006 | 0.00 | 0 |
| GCLC | ENSG00000001084 | 0.00 | 0 |
| IFNK | ENSG00000147896 | 0.00 | 0 |
| HSD17B3 | ENSG00000130948 | 0.00 | 0 |
| APOO | ENSG00000184831 | 0.00 | 0 |
| SLC25A33 | ENSG00000171612 | 0.00 | 0 |
| HIPK1 | ENSG00000163349 | 0.03 | 1 |
| CYP2C8 | ENSG00000138115 | 0.00 | 0 |
| BRSK2 | ENSG00000174672 | 0.00 | 0 |
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