Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| PARP16 | ENSG00000138617 | 0.00 | 0 |
| SEC11A | ENSG00000140612 | 0.00 | 0 |
| HSD3B7 | ENSG00000099377 | 0.00 | 0 |
| ST3GAL2 | ENSG00000157350 | 0.00 | 0 |
| MBTPS1 | ENSG00000140943 | 0.00 | 0 |
| RHBDL3 | ENSG00000141314 | 0.00 | 0 |
| KCNH4 | ENSG00000089558 | 0.00 | 0 |
| SEC11C | ENSG00000166562 | 0.00 | 0 |
| LMAN1 | ENSG00000074695 | 0.09 | 1 |
| BCL2 | ENSG00000171791 | 0.00 | 0 |
| CYP4F8 | ENSG00000186526 | 0.00 | 0 |
| CPT1C | ENSG00000169169 | 0.00 | 0 |
| HTRA2 | ENSG00000115317 | 0.00 | 0 |
| CHST10 | ENSG00000115526 | 0.00 | 0 |
| SMPD4 | ENSG00000136699 | 0.00 | 0 |
| UGT1A6 | ENSG00000167165 | 0.00 | 0 |
| ENTPD6 | ENSG00000197586 | 0.00 | 0 |
| ABHD12 | ENSG00000100997 | 0.00 | 0 |
| BPI | ENSG00000101425 | 0.00 | 0 |
| TMPRSS3 | ENSG00000160183 | 0.00 | 0 |
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