Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| CFD | ENSG00000197766 | 0.00 | 0 |
| MAP2K2 | ENSG00000126934 | 0.06 | 1 |
| KLK10 | ENSG00000129451 | 0.00 | 0 |
| RASGRP3 | ENSG00000152689 | 0.00 | 0 |
| ATP6V1B1 | ENSG00000116039 | 0.00 | 0 |
| IGKV3-11 | ENSG00000241351 | 0.00 | 0 |
| IGKV4-1 | ENSG00000211598 | 0.00 | 0 |
| IGKV1-5 | ENSG00000243466 | 0.00 | 0 |
| IGKV3-15 | ENSG00000244437 | 0.00 | 0 |
| IGKV3-20 | ENSG00000239951 | 0.00 | 0 |
| IGKV2-30 | ENSG00000243238 | 0.00 | 0 |
| IGKV1-39 | ENSG00000242371 | 0.00 | 0 |
| IGKV1D-16 | ENSG00000241244 | 0.00 | 0 |
| FBLN7 | ENSG00000144152 | 0.00 | 0 |
| CASP10 | ENSG00000003400 | 0.03 | 1 |
| PDYN | ENSG00000101327 | 0.00 | 0 |
| SNAP25 | ENSG00000132639 | 0.00 | 0 |
| PLCG1 | ENSG00000124181 | 0.06 | 2 |
| LIPI | ENSG00000188992 | 0.00 | 0 |
| GGTLC3 | ENSG00000274252 | 0.00 | 0 |
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