Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| SERPINE2 | ENSG00000135919 | 0.00 | 0 |
| SPINT1 | ENSG00000166145 | 0.03 | 1 |
| ECEL1 | ENSG00000171551 | 0.00 | 0 |
| AGRN | ENSG00000188157 | 0.00 | 0 |
| ENOX1 | ENSG00000120658 | 0.00 | 0 |
| SLC12A6 | ENSG00000140199 | 0.00 | 0 |
| CSPG5 | ENSG00000114646 | 0.00 | 0 |
| SSR1 | ENSG00000124783 | 0.00 | 0 |
| MST1R | ENSG00000164078 | 0.00 | 0 |
| ATP7B | ENSG00000123191 | 0.00 | 0 |
| CDH3 | ENSG00000062038 | 0.00 | 0 |
| EPHB2 | ENSG00000133216 | 0.00 | 0 |
| TNFRSF11A | ENSG00000141655 | 0.00 | 0 |
| ENPP1 | ENSG00000197594 | 0.00 | 0 |
| MC1R | ENSG00000258839 | 0.00 | 0 |
| FKRP | ENSG00000181027 | 0.00 | 0 |
| KCNJ14 | ENSG00000182324 | 0.00 | 0 |
| GRIN2D | ENSG00000105464 | 0.00 | 0 |
| SLC7A6 | ENSG00000103064 | 0.00 | 0 |
| TRPM4 | ENSG00000130529 | 0.00 | 0 |
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