Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| ANGPTL5 | ENSG00000187151 | 0.00 | 0 |
| MMP8 | ENSG00000118113 | 0.00 | 0 |
| SIAE | ENSG00000110013 | 0.00 | 0 |
| OR2W6P | ENSG00000168126 | 0.00 | 0 |
| C1R | ENSG00000159403 | 0.00 | 0 |
| MFAP5 | ENSG00000197614 | 0.00 | 0 |
| CELA1 | ENSG00000139610 | 0.00 | 0 |
| OR1B1 | ENSG00000280094 | 0.00 | 0 |
| OTOG | ENSG00000188162 | 0.00 | 0 |
| PROZ | ENSG00000126231 | 0.00 | 0 |
| RNASE9 | ENSG00000188655 | 0.00 | 0 |
| RNASE13 | ENSG00000206150 | 0.00 | 0 |
| DHRS4L2 | ENSG00000187630 | 0.00 | 0 |
| CMA1 | ENSG00000092009 | 0.00 | 0 |
| GZMH | ENSG00000100450 | 0.00 | 0 |
| PGF | ENSG00000119630 | 0.00 | 0 |
| IGKV5-2 | ENSG00000211599 | 0.00 | 0 |
| SCG3 | ENSG00000104112 | 0.00 | 0 |
| MAP2K1 | ENSG00000169032 | 0.30 | 2 |
| CES1 | ENSG00000198848 | 0.00 | 0 |
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