Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| PRSS41 | ENSG00000215148 | 0.00 | 0 |
| ADAMTS14 | ENSG00000138316 | 0.00 | 0 |
| MMRN2 | ENSG00000173269 | 0.00 | 0 |
| LIPK | ENSG00000204021 | 0.00 | 0 |
| LIPN | ENSG00000204020 | 0.00 | 0 |
| OR1P1 | ENSG00000262085 | 0.00 | 0 |
| LIPA | ENSG00000107798 | 0.00 | 0 |
| IDE | ENSG00000119912 | 0.00 | 0 |
| SLK | ENSG00000065613 | 0.05 | 1 |
| OR1D4 | ENSG00000255095 | 0.00 | 0 |
| DEAF1 | ENSG00000177030 | 0.00 | 0 |
| MUC5B | ENSG00000117983 | 0.00 | 0 |
| OLFML1 | ENSG00000183801 | 0.00 | 0 |
| OVCH2 | ENSG00000183378 | 0.00 | 0 |
| SAA4 | ENSG00000148965 | 0.00 | 0 |
| TCN1 | ENSG00000134827 | 0.00 | 0 |
| OR3A4P | ENSG00000180068 | 0.00 | 0 |
| GPHA2 | ENSG00000149735 | 0.00 | 0 |
| SLC22A20 | ENSG00000197847 | 0.00 | 0 |
| CTSC | ENSG00000109861 | 0.00 | 0 |
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