Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| ACLY | ENSG00000131473 | 0.04 | 1 |
| OR11H7 | ENSG00000258806 | 0.00 | 0 |
| NMT1 | ENSG00000136448 | 0.00 | 0 |
| OR4E1 | ENSG00000276240 | 0.00 | 0 |
| ARSG | ENSG00000141337 | 0.00 | 0 |
| ADGRE4P | ENSG00000268758 | 0.00 | 0 |
| TWSG1 | ENSG00000128791 | 0.00 | 0 |
| TTR | ENSG00000118271 | 0.00 | 0 |
| AC005255.6 | ENSG00000172148 | 0.00 | 0 |
| SERPINB4 | ENSG00000206073 | 0.00 | 0 |
| GZMM | ENSG00000197540 | 0.00 | 0 |
| PIP5K1C | ENSG00000186111 | 0.00 | 0 |
| INSL3 | ENSG00000248099 | 0.00 | 0 |
| NCAN | ENSG00000130287 | 0.00 | 0 |
| ACTN4 | ENSG00000130402 | 0.02 | 1 |
| OR1F12 | ENSG00000220721 | 0.00 | 0 |
| OR2J1 | ENSG00000204702 | 0.00 | 0 |
| KIR2DS4 | ENSG00000221957 | 0.00 | 0 |
| QPCT | ENSG00000115828 | 0.00 | 0 |
| PCYOX1 | ENSG00000116005 | 0.00 | 0 |
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