Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| TPSAB1 | ENSG00000172236 | 0.00 | 0 |
| PRSS22 | ENSG00000005001 | 0.00 | 0 |
| MMP25 | ENSG00000008516 | 0.00 | 0 |
| DNASE1 | ENSG00000213918 | 0.00 | 0 |
| PRSS36 | ENSG00000178226 | 0.00 | 0 |
| NTN1 | ENSG00000065320 | 0.00 | 0 |
| CCL7 | ENSG00000108688 | 0.00 | 0 |
| GH2 | ENSG00000136487 | 0.00 | 0 |
| FASN | ENSG00000169710 | 0.07 | 1 |
| CSNK1D | ENSG00000141551 | 0.00 | 0 |
| PRKACA | ENSG00000072062 | 0.00 | 0 |
| MRC1 | ENSG00000260314 | 0.00 | 0 |
| PRKCE | ENSG00000171132 | 0.00 | 0 |
| ZAP70 | ENSG00000115085 | 0.00 | 0 |
| CST9L | ENSG00000101435 | 0.00 | 0 |
| WFDC2 | ENSG00000101443 | 0.00 | 0 |
| CTSA | ENSG00000064601 | 0.00 | 0 |
| SPPL2B | ENSG00000005206 | 0.00 | 0 |
| WNT7B | ENSG00000188064 | 0.00 | 0 |
| SPINK8 | ENSG00000229453 | 0.00 | 0 |
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