Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| SLC37A1 | ENSG00000160190 | 0.00 | 0 |
| IL22RA2 | ENSG00000164485 | 0.00 | 0 |
| ATP13A5 | ENSG00000187527 | 0.00 | 0 |
| PRSS58 | ENSG00000258223 | 0.00 | 0 |
| PENK | ENSG00000181195 | 0.00 | 0 |
| BMP15 | ENSG00000130385 | 0.00 | 0 |
| SMPD2 | ENSG00000135587 | 0.00 | 0 |
| NODAL | ENSG00000156574 | 0.00 | 0 |
| HILPDA | ENSG00000135245 | 0.00 | 0 |
| P4HA1 | ENSG00000122884 | 0.00 | 0 |
| FOLR3 | ENSG00000110203 | 0.00 | 0 |
| INHBC | ENSG00000175189 | 0.00 | 0 |
| INHBE | ENSG00000139269 | 0.00 | 0 |
| AQP7 | ENSG00000165269 | 0.00 | 0 |
| ERO1L | ENSG00000197930 | 0.00 | 0 |
| FAM20A | ENSG00000108950 | 0.00 | 0 |
| AZU1 | ENSG00000172232 | 0.00 | 0 |
| CDCP2 | ENSG00000157211 | 0.00 | 0 |
| KLK12 | ENSG00000186474 | 0.00 | 0 |
| PDE3B | ENSG00000152270 | 0.08 | 1 |
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