Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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| HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
| HVCN1 | ENSG00000122986 | 0.00 | 0 |
| UGGT1 | ENSG00000136731 | 0.00 | 0 |
| SPNS2 | ENSG00000183018 | 0.00 | 0 |
| KLK5 | ENSG00000167754 | 0.00 | 0 |
| VIP | ENSG00000146469 | 0.00 | 0 |
| LILRA4 | ENSG00000239961 | 0.00 | 0 |
| SLC4A5 | ENSG00000188687 | 0.00 | 0 |
| TGFB2 | ENSG00000092969 | 0.00 | 0 |
| COMT | ENSG00000093010 | 0.00 | 0 |
| PDE2A | ENSG00000186642 | 0.00 | 0 |
| KLK11 | ENSG00000167757 | 0.00 | 0 |
| KLK14 | ENSG00000129437 | 0.00 | 0 |
| TNFSF10 | ENSG00000121858 | 0.00 | 0 |
| COL25A1 | ENSG00000188517 | 0.00 | 0 |
| SFTPB | ENSG00000168878 | 0.00 | 0 |
| DST | ENSG00000151914 | 0.17 | 1 |
| IGLL5 | ENSG00000254709 | 0.00 | 0 |
| TAS2R5 | ENSG00000127366 | 0.00 | 0 |
| GDF9 | ENSG00000164404 | 0.00 | 0 |
| TULP1 | ENSG00000112041 | 0.00 | 0 |
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