Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
GRIN2CENSG00000161509                                                                                                                                    
SECTM1ENSG00000141574                                                                                                                                    
SLC14A2ENSG00000132874                                                                                                                                    
CLEC4MENSG00000104938                                                                                                                                    
SLC7A9ENSG00000021488                                                                                                                                    
KIRREL2ENSG00000126259                                                                                                                                    
SLC3A1ENSG00000138079                                                                                                                                    
ICOSENSG00000163600                                                                                                                                    
ADAM23ENSG00000114948                                                                                                                                    
CHRNGENSG00000196811                                                                                                                                    
PTPRTENSG00000196090                                                                                                                                    
IFNGR2ENSG00000159128                                                                                                                                    
DSCAMENSG00000171587                                                                                                                                    
SLC16A8ENSG00000100156                                                                                                                                    
SCN5AENSG00000183873                                                                                                                                    
TLR6ENSG00000174130                                                                                                                                    
TMPRSS11BENSG00000185873                                                                                                                                    
TMPRSS11EENSG00000087128                                                                                                                                    
GYPBENSG00000250361                                                                                                                                    
SLC6A3ENSG00000142319                                                                                                                                    

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