Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
LAG3ENSG00000089692                                                                                                                                    
PTPROENSG00000151490                                                                                                                                    
SLC38A2ENSG00000134294                                                                                                                                    
KLENSG00000133116                                                                                                                                    
SLC39A2ENSG00000165794                                                                                                                                    
FLVCR2ENSG00000119686                                                                                                                                    
DLL4ENSG00000128917                                                                                                                                    
DUOX1ENSG00000137857                                                                                                                                    
NRG4ENSG00000169752                                                                                                                                    
CHRNB4ENSG00000117971                                                                                                                                    
UMODENSG00000169344                                                                                                                                    
ZP2ENSG00000103310                                                                                                                                    
ITGADENSG00000156886                                                                                                                                    
TRPV3ENSG00000167723                                                                                                                                    
RAMP2ENSG00000131477                                                                                                                                    
CD300LGENSG00000161649                                                                                                                                    
SLC16A6ENSG00000108932                                                                                                                                    
CD300AENSG00000167851                                                                                                                                    
CD300CENSG00000167850                                                                                                                                    
CD300LFENSG00000186074                                                                                                                                    

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