Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
GRIN2AENSG00000183454                                                                                                                                    
GPRC5BENSG00000167191                                                                                                                                    
OR4D2ENSG00000255713                                                                                                                                    
ADGRL1ENSG00000072071                                                                                                                                    
LPAR2ENSG00000064547                                                                                                                                    
FPR2ENSG00000171049                                                                                                                                    
KIR2DL4ENSG00000189013                                                                                                                                    
LCTENSG00000115850                                                                                                                                    
KCNE1ENSG00000180509                                                                                                                                    
UMODL1ENSG00000177398                                                                                                                                    
TRPM2ENSG00000142185                                                                                                                                    
CX3CR1ENSG00000168329                                                                                                                                    
GRM2ENSG00000164082                                                                                                                                    
HTR1FENSG00000179097                                                                                                                                    
ACPPENSG00000014257                                                                                                                                    
GPR87ENSG00000138271                                                                                                                                    
GABRA1ENSG00000022355                                                                                                                                    
HTR1EENSG00000168830                                                                                                                                    
GPR6ENSG00000146360                                                                                                                                    
GPRC6AENSG00000173612                                                                                                                                    

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