Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TMX4ENSG00000125827                                                                                                                                    
SLC12A5ENSG00000124140                                                                                                                                    
KCNG1ENSG00000026559                                                                                                                                    
TDGF1ENSG00000241186                                                                                                                                    
SLC10A6ENSG00000145283                                                                                                                                    
NOTCH4ENSG00000204301                                                                                                                                    
PKHD1ENSG00000170927                                                                                                                                    
ADCY1ENSG00000164742                                                                                                                                    
KCND2ENSG00000184408                                                                                                                                    
ATP6V0A4ENSG00000105929                                                                                                                                    
TYRP1ENSG00000107165                                                                                                                                    
SLC24A2ENSG00000155886                                                                                                                                    
NOX1ENSG00000007952                                                                                                                                    
SLC15A3ENSG00000110446                                                                                                                                    
KCNK7ENSG00000173338                                                                                                                                    
KCNH5ENSG00000140015                                                                                                                                    
KCNK13ENSG00000152315                                                                                                                                    
KCNH6ENSG00000173826                                                                                                                                    
KCNJ15ENSG00000157551                                                                                                                                    
MFSD8ENSG00000164073                                                                                                                                    

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