Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
KIR2DL1ENSG00000125498                                                                                                                                    
KIR3DL2ENSG00000240403                                                                                                                                    
ABCG5ENSG00000138075                                                                                                                                    
TGFAENSG00000163235                                                                                                                                    
CD8AENSG00000153563                                                                                                                                    
IL18RAPENSG00000115607                                                                                                                                    
CHRNA4ENSG00000101204                                                                                                                                    
TMPRSS6ENSG00000187045                                                                                                                                    
MUC13ENSG00000173702                                                                                                                                    
TMPRSS11DENSG00000153802                                                                                                                                    
EREGENSG00000124882                                                                                                                                    
BTCENSG00000174808                                                                                                                                    
GABRB2ENSG00000145864                                                                                                                                    
BTN3A2ENSG00000186470                                                                                                                                    
GRIK2ENSG00000164418                                                                                                                                    
KELENSG00000197993                                                                                                                                    
NRG1ENSG00000157168                                                                                                                                    
IL1RAPL1ENSG00000169306                                                                                                                                    
GPR119ENSG00000147262                                                                                                                                    
IL9RENSG00000124334                                                                                                                                    

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