Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
OR4E2ENSG00000221977                                                                                                                                    
SSTR1ENSG00000139874                                                                                                                                    
GPR68ENSG00000119714                                                                                                                                    
BDKRB2ENSG00000168398                                                                                                                                    
BDKRB1ENSG00000100739                                                                                                                                    
OR4N4ENSG00000183706                                                                                                                                    
CHRM5ENSG00000184984                                                                                                                                    
OR4F15ENSG00000182854                                                                                                                                    
OR1F1ENSG00000168124                                                                                                                                    
OR2C1ENSG00000168158                                                                                                                                    
GPR139ENSG00000180269                                                                                                                                    
OR1G1ENSG00000183024                                                                                                                                    
OR3A2ENSG00000221882                                                                                                                                    
OR1E1ENSG00000180016                                                                                                                                    
OR3A3ENSG00000159961                                                                                                                                    
OR1E2ENSG00000127780                                                                                                                                    
CCR10ENSG00000184451                                                                                                                                    
GALR2ENSG00000182687                                                                                                                                    
GALR1ENSG00000166573                                                                                                                                    
OR2Z1ENSG00000181733                                                                                                                                    

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