Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CHD8ENSG00000100888                                  1    1                                                                                              
METTL22ENSG00000067365                                                                                                                                    
PRMT7ENSG00000132600                                                                                                                                    
CHD3ENSG00000170004                                                                                                                          1          
SIRT7ENSG00000187531                                                                                                                                    
ASXL3ENSG00000141431                                                                                                                                    
SIRT6ENSG00000077463                                                                                                                                    
SMARCA4ENSG00000127616      1                                            1        1        1                                                                  
TDRD12ENSG00000173809                                                                                                                                    
KMT2BENSG00000272333                                                                                                                          1          
TDRD15ENSG00000218819                                                                                                                                    
MSH6ENSG00000116062                                                                                                                                    
CHD6ENSG00000124177                                                                                                                                    
TCF20ENSG00000100207                                                                                                                                    
WHSC1ENSG00000109685                                                                                                                                    
PRMT9ENSG00000164169                                                                                                                                    
CHD1ENSG00000153922                                                                                                                                    
PRDM6ENSG00000061455                                                                                                                                    
JARID2ENSG00000008083                                                                                                                                    
L3MBTL3ENSG00000198945                                                                                                                                    

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