Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SIRT5ENSG00000124523                                                                                                                                    
SHPRHENSG00000146414                                                                                                                                    
KDM6AENSG00000147050      1                        1        1            1                                1        1                                          
UTYENSG00000183878                                                                                                                                    
CDY2BENSG00000129873                                                                                                                                    
CDY2AENSG00000182415                                                                                                                                    
KDM5DENSG00000012817                                                                                                                                    
CDY1BENSG00000172352                                                                                                                                    
CDY1ENSG00000172288                                                                                                                                    
CHD5ENSG00000116254                                                                                                                                    
TDRD5ENSG00000162782                                                                                                                                    
KDM5BENSG00000117139                                                                                                                                    
SFMBT2ENSG00000198879                                                                                                                                    
RAG2ENSG00000175097                                                                                                                                    
KDM5AENSG00000073614                                                                                                                                    
METTL20ENSG00000139160                                                                                                                                    
SIRT4ENSG00000089163                                                                                                                                    
KDM2BENSG00000089094                                                                                                                                    
METTL21CENSG00000139780                                                                                                                                    
ING1ENSG00000153487                                                                                                                          1          

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